Zetasizer Ultra is the most efficient combined system of DLS and ELS, incorporating NIBS® and MADLS technologies to measure particle and molecule sizes. NIBS technology offers versatility and sensitivity to measure a wide range of concentrations. MADLS technology, in turn, allows you to view the size distribution of your samples in higher resolution for more critical measurements.
With the extension of MADLS, it is possible to directly analyze the concentration of particles. It does not need calibration and is compatible with various materials, in addition to requiring little or no dilution and being quick to use. For these reasons, it is the ideal separation technique. This feature is unique to Zetasizer Ultra. It can be applied even to virus samples and VLPs, previously complicated to measure.
The Zetasizer Ultra also offers the most sensitive measurements of zeta potential and electrophoretic mobility with M3-PALS technology. Used with our patented diffusion barrier method, our foldable, disposable and accessible hair cells make it possible to measure very low volumes without direct contact between the electrode and the sample. The results of these measurements are excellent indicators of the stability of the sample and / or the propensity to aggregate.
The addition of Constant Current Mode to measure electrophoretic mobility and zeta potential in high conductivity media reduces errors that can be associated with electrode polarization at higher ionic concentrations.